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Section IV: |
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A 71
year-old female reported with a diffuse, large, ulcerated, asymptomatic
dark patch in the nose;
Members who helped in diagnosing the case as Basal Cell Carcinoma: Alka D kale D/D : trichoepithelioma -basal cell carcinoma --neuro endocrine carcinoma -spitz naevus
Gururaja.Rao This is a case of Basal cell carcinoma
Sook Woo It looks like an infiltrating SCC to me. It looks like it is from skin rather than nasal mucosa.
Dr. Ricardo Moreno I think that is a kind of Basocellular carcinoma.
Dr Susmita Saxena Basal Cell Carcinoma
Pablo Agustin Vargas The histological figures suggest the diagnosis of Infiltrating Basal Cell Carcinoma.
Mei Syafriadi Proliferation of epithelial basal cell nest that related to the surface, some part calcification, keratinization and fibrous stromal, invasive to adipose tissue. some pattern showed hair follicle-like origin. Dx Basal Cell Ca. DD: Trichoephithelioma
Chong Huat Siar My favoured diagnosis is basal cell carcinoma. Thank you for sharing with us this interesting case. Best regards, Siar
G N Mohanty Uniform looking cells arranged in sheets with peripheral pallisading of nuclei, melanin pigmentation. Squamous differentiation focally.? perinural spread.it can be Basal cell carcinoma.Site is very suggeastive also.
Dr.Ilana Kaplan Basaloid SCC? |
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A 20 year old male reported with a recurrent pedunculated growth of 1 month
duration in lower anterior alveolus region. Swelling is firm and there is
bleeding on probing.
Got mixed resposes for this case. Most members either suggested either solitary fibrous tumour or pyogenic granuloma, however needed special stains to diagnose: Paulo Tambasco Hemangioendothelioma
Prof.Paolo Boccato Possible polimorphous low grade carcinoma of the salivary glands
Sook woo The micrographs do not show if the tumor is infiltrative or encapsulated. It is hard to tell. I can only say it looks like a spindle cell vascular proliferation at this power but cannot tell if it is benign, malignant or of intermediate biologic potential.
D Gnepp ? Solitary fibrous tumor; need battery of immuno stains; R/O out sarcomatoid squamous Ca, spindle cell melanoma, etc
Pablo Agustin Vargas The quality of photomicrographs is barely adequate. However, my diagnosis opinion is a mesenchymal neoplasm and an immunohistochemical study is essential to perform a precise diagnosis.
James Cade Pyogenic granuloma
Wang Li Vescular Epulis
Román Carlos The quality of the histology is poor however it is suggestive of SOLITARY FIBROUS TUMOR
Dr. Alka Kale Slide reviewed shows fibro-cellular stroma, Inflammatory component, Many blood vessels-Pyogenic granuloma
Dr. Vinay Hazarey May be Kaposi sarcoma.
Dr Priya Pyogenic granuloma(presence of mitotic figures & inflammatory comonent)
Chuck Tomich This could be a reactive myofibroblastic proliferation. I'd do some immunostains.
Sourav Bhattacharya Fibrous histiocytoma
Dr. Narendra Nath Singh It appears to be HEMANGIOpericytoma. suggested special stain silver stains for confirmation
Dr Gita Rezvani Fibromatosis
Dr. G.S.kumar All the 3 histopath. pictures show either spindle or ovoid cells with a certain degree of malignant features. these cells are not lining the bld. vessels, but they are close to it. if both components- spindle &ovoid cells truly exist(not due to sectioning),then one can think of fibrous Histiocytoma, otherwise you have to confirm these cells as endothelial or pericytes and then your diagnosis could be haemangiompericytoma/endothelioma
Magesh K.T. shows plenty of endothelial cellproliferation. may be pyogenic granulomma
Dr. Archana The Clinical history and the photomicrographs go in favour of Peripheral Giant Cell Granuloma
Indraneel Bhattacharyya Most likely a lesion of vascular origin i.e hemangiopericytoma I would perform a CD 34 stain
Dr. Jaimin Patel fibrosarcoma. i think more fields should be examined. prominent and atypical cells seen, with pleomorphism.
Manish The photomicrograph of the high power view of the sections shows spindle shaped cells showing hyperchromatic nucleus and prominent nucleoli and also they appear to originate from the wall of the blood vessel...could be a case of leiomyosarcoma
Charles E. Tomich My differential diagnosis includes a reactive myofibroblastic lesion and a vascular lesion. I recommend appropriate immunostains.
Dr Kalpana Sharma pyogenic granuloma |
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A 52 year old female patient reported with a firm swelling in the left maxilla extending from canine to second molar region. On radiographs it was a round 3.5 cm diameter lesion with mixed radiolucency and radiopacity with a well defined border.
Dr. Vinay Hazarey Desmoplastic Ameloblastoma
Pablo Agustin Vargas Ameloblastoma with acanthomatous and desmoplastic areas.
Nagamani Narayana desmoplastic ameloblastoma
Carl M. Allen, DDS desmoplastic ameloblastoma
Kurt Summersgill Focus, resolution, and magnification are less than adequate for these images. That stated, it looks like ameloblastoma.
John Wright Dangerous offering a definitive dx because the photomics are not diagnostic quality, but some features suggest desmoplastic ameloblastoma
Indraneel Bhattacharyya Most likely an odontogenic tumor with the presence of odontogenic epithelial islands and also the dense fibrous stroma I would favor a desmoplastic ameloblastoma. However, the radiographic picture puzzles me since there is no evidence of calcified structures at least on the provided photos.
W M Tilakaratne Desmoplastic ameloblastoma
Dr Baalaji acanthomatic ameloblastoma
Dr Malathi ameloblastoma-
Aditi Bhattacharya Desmoplastic Ameloblastoma
Hedley Coleman The features suggest a diagnosis of desmoplastic ameloblastoma
Sook-Bin Woo Most of the photomics are out of focus, but it looks like a schirrous/desmoplastic ameloblastoma. The history of mixed lucent/opaque lesion is typical.
Ravi Shetty If You want to call it Desmoplastic ameloblastomas, check the radiographs to rule out the tumour perforating the cortex and spilling in the soft tissue. X-rays are must
Paul Freedman Desmoplastic ameloblastoma
Mala Kamboj To me it looks like a well polarised basal cell lining surrounded with excessive collagen in the connective tissue stroma. It could be Desmoplastic Ameloblastoma.
Susan Zunt Ameloblastoma with desmoplasia, based on these images.
Lewei Zhang Ameloblastoma
Samadara It is a Desmoplastic Ameloblastoma
Sivapathasundharam B Diagnosis: Desmoplastic Amelobalstoma. In this case the site and radiographic appea rence (Mixed radio-opacity and Lucency,mimicking fibroosseous lesion)is typical. Histologically mature fibrous tissue, and diamond shaped epithelial islands some of which have typical kite-tail like extension. However a recurrent amelobalstoma should be kept in mind if mature fibrous tissue alone is encounterd.
Dr. Behnam Eslami In histological features it looks like an epithelial odontogenic tumor. Unfortunately I don't have good pictures but it dosen't seem malignant (actually it is also well defined). With radiological data the lesion is mostly compatible with: Desmoplastic Ameloblastoma.
Benjamin Martinez, MS Desmoplastic ameloblastoma.
C.D. Daniel Quezada Rivera Desmoplasic ameloblastoma
Yeshwant B. Rawal Ameloblastoma. Probably Desmoplatic Variant.
M. Kahn desmoplastic ameloblastoma
Amos Buchner Desmoplastic Ameloblastoma
Catherine M. Flaitz Desmoplastic ameloblastoma
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A 45 year old female reported with a swelling in the posterior region of the oral cavity on the left side. It was 4x3 cm radiolucent lesion with irregular borders in the ramus of the mandible and of 6 months duration. Buccal and lingual cortical plate expansion was present.
Lan Su clear cell odontogenic carcinoma, rule out central mucoepidermoid carcinoma
Dr. Dinesh Clear cell odontogenic carcinoma
Chaitanya odontogenic carcinoma
Carl Allen This appears to be an odontogenic epithelial neoplasm, and the features are most consistent with a malignant process. Clear cell odontogenic carcinoma or ameloblastic carcinoma with a clear cell component would be the most likely diagnosis, based on these photomicrographs.
Susan Zunt, DDS, MS Clear cell odontogenic carcinoma
Sook-bin woo Hard to tell. Lots like carcinoma and the d/dx would include, odontogenic carcinoma, clear cell odontogenic carcinoma or even mucoepidermoid carcinoma. Stains would help.
Raghu AR For me the first impression was a clear cell odontogenic tumor, but from the photomicrograph i see in some areas a lot of cytological atypia which is not a typical of Clear Cell Odontogenic tumor/ carcinoma. Kindly do a PAS/Mucicarmine and rule of Mucoepidermoid carcinoma
Somsri R Sirivej: I have a feeling this is a case of carcinoma. With a lot of clear cells and epidermoid like cell, I think it's intraosseous mucoepidermoid carcinoma.
Benjamin Martinez, MS Consistent with metastatic clear cells adenocarcinoma, r/o: kidney, thyroid as origin of the primary tumor. Also clear cell odontogenic carcinoma could be considered but there are large quantity of vessels and suggested more as metastatic. |
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Case 26: |
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A male patient aged 30 years came for extraction. A routine
radiograph revealed a radiolucent lesion. On surgical exploration the lesion was
found to be a cystic lesion. It was curetted and was found to have a friable
lining. The Cheesy material expulsed through the lesion was diagnosed as OKC. Members Interpretations of the case
Nirmala N Rao
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Case 28: Members who interpreted the case as Clear Cell Odontogenic Carcinoma, however suggested special stains to rule out Mucoepidermoid Carcinoma or Metastatic Renal cell Carcinoma
Mehraj Shams
Farzan Naveen
Vydehi Institute,Blore
Dr.Kraisorn Sappayatosok / Dr. Kittipong
Dhanuthai
Susmita Saxena
Smitha.T
Mohan Kumar K P
Harshvardhan
Elias Romero
Gururaj patil
Sachin Sarode
Premdeep Gandhi
K.Karunakaran
Mei Syafriadi
Alberto
J. Fantasia
Indraneel Bhattacharyya
Mario Nava
Gerardo Meza
Carl M. Allen, DDS
Atilio Silva
Jaana Hagström
G Galla
Rafik Abdelsayed
Susan Zunt
Darunee Jintakanon
Jung-Hoon Yoon
Rogelio
Kalu Ogbureke
Bernardo Cruz
Mabokesone
Ney Soares De Araujo
Nasser Said-Al-Naief
Charles E. Tomich
Yeshwant B. Rawal
Claudio Molina
James Cade |
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Send your cases to: drsunilkumar@rediffmail.com |
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