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| Case 33: | ||||||||||||||||||||||||||
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A 60-year-old female presented with a painless growth over the right buccal mucosa of 3 months duration. History revealed that the growth gradually increased to the present size, measuring 1.5x1 cm in diameter. Her past medical history was not significant. On examination, an indurated ulcer was present in the buccal commissure extending to the lower lip. There was no associated lymphadenopathy. A provisional diagnosis of squamous cell carcinoma was made. The lesion was excised and sent for HP examination. [No pre-operative biopsy was done].
Histopathological examination of excised specimen was examined
routinely. The lesion microscopically was made of gland-like
proliferation characterized by long, slender filiform
micropapilla with secondary and tertiary tufts but without a
connective tissue core projecting into a cystic space. The cells
that lined up the papilla are large cuboidal cells, the nuclei
of which showed dispersed chromatin and prominent nucleoli.
Increased mitotic figures, more than 5 per high power field were
found Figure [A, B, C]. |
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Post your comments of possible histopathological diagnosis here : |
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